Mar 31, Peliosis hepatis (PH) is a rare condition characterized by tumor-like liver lesions composed of multiple blood-filled cavities. The etiology and. Peliosis hepatis is a rare, benign disorder causing sinusoidal dilatation and the presence of multiple blood-filled lacunar spaces within the liver. We report a. Oct 20, Peliosis hepatis, another reactive vascular process which radiologically . Peliosis hepatis can be diagnosed at liver imaging, based on characteristic features Online ISBN ; eBook Packages Medicine.
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Mar 17, Peliosis hepatis is a rare vascular condition of the liver characterized by a proliferation of the sinusoidal hepatic capillaries that results in cystic. OBJECTIVE. It is important to recognize the imaging characteristics of peliosis hepatis because peliotic lesions mimic several different types of focal hepatic. Cases of peliosis hepatis have been described in young patients treated with AZA after binge alcohol use. Acute SOS has been reported after 14 months of.
Table of Contents
Pathogenetically, Bartonella modulate vascular morphogenesis and induce endothelial cell migration and proliferation. Peliosis hepatis, another reactive vascular process which radiologically resembles liver tumors, is characterized by focal or diffuse cystic blood-filled spaces mainly localized in parenchyma.
Peliotic lesions show a loss of endothelial lining and an effacement of the perisinusoidal reticulin network. Peliosis hepatis can be induced by a wide array of factors, including infections and drugs.
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Electron microscopical study of 14 cases. MR and diffusion-weighted MR-imaging findings of an atypical case. Association with angioimmunoblastic lymphadenopathy and severe hypoxemia. An immunohistochemical and clinicopathologic study of five cases.
Lessons: PH should always be recognized in the differentiation of liver lesions, particularly indistinctive lesion s without any history of liver-related diseases. Keywords: differential diagnosis, imaging, liver lesions, peliosis hepatis 1. Introduction Peliosis hepatis PH is a rare condition characterized by tumor-like liver lesions composed of multiple blood-filled cavities.
The etiology and pathogenesis of PH are not clear.
Reported data showed that PH might be associated with numerous causes, such as cytotoxic drug, gamma-ray, bacterial or viral infection, immunodeficiency, and so on. Therefore, it is hard to be differentiated from the other similar diseases.
In this study, we reported 2 unusual cases presented with liver lesions in imaging without a history of liver disease and were eventually diagnosed as PH by histopathology. Case report 2.
Case 1 A year-old female, with 2 months history of fatigue, anorexia, and abdominal distention, was admitted to our hospital. An upper abdominal contrast-enhanced computed tomography CT scanning at the local hospital identified an incrassate and dropsical gallbladder wall, by which an acute episode of chronic cholecystitis was diagnosed initially. In addition to the gallbladder abnormality, hepatosplenomegaly and multiple lower-density lesions within the liver were found.
Medical record showed no history of viral hepatitis or bacterial infections in the liver. Abdominal palpation revealed a slight discomfort in the right upper quadrant, as well as hepatosplenomegaly.
The patient was sensitive to percussion on the hepatic region with negative Murphy sign. Thrombocytopenia was identified with a platelet count of 6.
Other laboratory examinations witnessed normal white blood cell count, hemoglobin, blood electrolytes, and prothrombin time.Case 1 A year-old female, with 2 months history of fatigue, anorexia, and abdominal distention, was admitted to our hospital. Case report 2. Peliosis hepatis is a rare, benign disorder causing sinusoidal dilatation and the presence of multiple blood-filled lacunar spaces within the liver.
Ultrasound guidance makes the jugular puncture easier and safer. Typical PH with mild hepatic fibrosis was recognized by histopathology Fig.
Liver biopsy remains essential for the diagnosis of some liver diseases, such as nonalcoholic steatohepatitis, abnormal liver tests from unknown origin, or autoimmune hepatitis.
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